中文名稱：干擾素β抗體
產(chǎn)品貨號：ZIKER-0787R
英文名稱：IFN-Beta/Ifnb1
別 名：Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFNB 1; IFNB; IFNB1; Interferon beta 1 fibroblast; Interferon beta precursor; MGC96956.
規(guī) 格 ：50ul 100ul 200ul
研究領(lǐng)域：腫瘤 細(xì)胞生物 免疫學(xué) 干擾素
抗體來源：Rabbit
克隆類型：Polyclonal
交叉反應(yīng)： Human,
產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量：20kDa
細(xì)胞定位：分泌型蛋白
性 狀：Lyophilized or Liquid
濃 度：1mg/ml
免 疫 原：KLH conjugated synthetic peptide derived from human IFN-Beta:101-187/187
亞 型：IgG
純化方法：affinity purified by Protein A
儲 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
產(chǎn)品介紹background:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
Function:
Has antiviral, antibacterial and anticancer activities.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Similarity:
Belongs to the alpha/beta interferon family.
SWISS:
P01574
Gene ID:
3456
Database links:
Entrez Gene: 3456 Human
Omim: 147640 Human
SwissProt: P01574 Human
Unigene: 93177 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β型干擾素(Interferon-β,IFN-β)是主要由成纖維細(xì)胞產(chǎn)生的細(xì)胞因子,屬于單一基因編碼產(chǎn)生的蛋白質(zhì),可通過干擾病毒RNA或DNA復(fù)制而抑制病毒生長,并可顯著增強(qiáng)NK細(xì)胞殺傷活性,通過促進(jìn)MHCⅠ類分子表達(dá)而增強(qiáng)CTL對病毒感染細(xì)胞的識別和殺傷作用.
