中文名稱(chēng)：血小板活化因子抗體

產(chǎn)品貨號(hào)：ZIKER-1119R

英文名稱(chēng)：PAF
別    名：platelet-activating factor; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate; 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine; 1-hexadecyl-2-acetyl, PAF(C16.  
規(guī)     格： 100ul  
產(chǎn)品類(lèi)型：藥物與化合物抗體 
研究領(lǐng)域：藥物及化合物  
抗體來(lái)源：Rabbit
克隆類(lèi)型：Polyclonal
交叉反應(yīng)： Rat, PAF
產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量：0.524kDa
性    狀：Lyophilized or Liquid
濃    度：1mg/ml
免 疫 原：KLH conjugated PAF: 
亞    型：IgG
純化方法：affinity purified by Protein A
儲(chǔ) 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹：background:
Platelet-activating factor, a compound that reduces inflammation by increasing permeability of blood vessels and contracting various involuntary muscles such as those in airways. It is a phospholipid with a wide range of proinflammatory actions, is immediately degraded and inactivated in vivo by PAF acetylhydrolase.

SWISS:
N/A

CAS:
74389-68-7

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

血小板活化因子（platelet-activating factor，PAF）是一種內(nèi)源性具有生物活性的磷脂。由中性粒細(xì)胞、血小板、肥大細(xì)胞、內(nèi)皮細(xì)胞和巨噬細(xì)胞產(chǎn)生。除早期發(fā)現(xiàn)它有強(qiáng)烈引起血小板聚集和脫顆粒作用外，近年來(lái)的研究發(fā)現(xiàn)它還具有廣泛的生物活性，作為一種獨(dú)特的細(xì)胞因子參與體內(nèi)多種生理、病理過(guò)程，包括激活中性粒細(xì)胞，使其聚集、趨化、釋放氧自由基和白三烯，抑制T細(xì)胞增殖，刺激B細(xì)胞合成IgG和IgE，抑制心肌收縮力，增加血管通透性，引起體循環(huán)血壓下降和肺動(dòng)脈高壓等。由于它具有廣泛的高強(qiáng)度的生物活性，故PAF被認(rèn)為是與過(guò)敏反應(yīng)有關(guān)的關(guān)鍵性介質(zhì)之一。