Synonyms :

BMP-2B, DVR4

Description :

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.

Catalog #:

120-05

Source :

HeLa cells

Purity :

Greater than 97% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.

Selected References :

Selected List of References Citing This Product

AA Sequence :

HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR

PubMed Link :

BMP-4

Country of Origin :

USA

Special Sizes: 
Many products can be ordered in custom sizes. Please click here to contact with your request.

Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.