PeproTech重組人GDF-11 貨號：120-11
PeproTech重組人GDF-11 貨號：120-11
PeproTech重組人GDF-11 貨號：120-11
產(chǎn)地 ：美國
品牌 :PeproTech
貨號： 120-11
規(guī)格：5μg/20μg/1mg
英文名： Recombinant Human GDF-11
保質(zhì)期： 1年以上
供應(yīng)商： 深圳子科生物科技有限公司
保存條件： -20℃
|
Synonyms :
|
Growth/Differentiation Factor-11, BMP-11
|
|
Description :
|
GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.
|
|
Catalog #:
|
120-11
|
|
Source :
|
E.coli
|
|
Purity :
|
Greater than 98% by SDS-PAGE gel and HPLC analyses.
|
|
Endotoxin Level :
|
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
|
|
Biological Activity :
|
The ED 50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED 50 for this effect is 0.08-0.10 μg/ml.
|
|
AA Sequence :
|
NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
|
|
PubMed Link :
|
GDF+AND+11
|
|
Country of Origin :
|
USA
|
|
|
|
|
|
|
Size A
|
5μg
|
|
|
|
|
|
Size B
|
20μg
|
5
|
|
|
|
|
Size C
|
1mg
|
00
|
|
|
|
|
|
|
|
|
|
Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.
|
|
|
Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
|
