PeproTech重組小鼠IL-13，貨號：210-13
PeproTech重組小鼠IL-13，貨號：210-13
PeproTech重組小鼠IL-13，貨號：210-13
產(chǎn)地； 美國
品牌： PeproTech
貨號： 210-13
規(guī)格：2μg/10μg/1mg
英文名： Recombinant Murine IL-13
CAS號： 無
數(shù)量： 大量
供應(yīng)商： PeproTech(派普泰克)
保存條件： -20oC
保質(zhì)期： 1年以上
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Synonyms :
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NC300 (Human) P600 (Murine)
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Description :
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IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.
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Catalog #:
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210-13
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Source :
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E.coli
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Purity :
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Greater than 98% by SDS-PAGE gel and HPLC analyses.
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Endotoxin Level :
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Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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Biological Activity :
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The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.
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Selected References :
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Selected List of References Citing This Product
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AA Sequence :
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MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
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PubMed Link :
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IL-13+AND+mouse
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Country of Origin :
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USA
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